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State-of-the-Art on Sleep Disorders, ED and Endothelial Dysfunction

Isr Med Assoc J. 2019 Jun;21(6):408-411.

Erectile Dysfunction,

Sleep Disorders, and Endothelial Function.

Konstantinovsky A1, Tamir S2, Katz G1, Tzischinsky O3, Kuchersky N1, Blum N4, Blum A4.


Department of Urology, Padeh Medical Center, Poriya, Israel.


Department of Human Health and Nutrition Sciences, Tel Hai Academic College, Galilee, Israel.


Department of Psychology, Max Stern Academic College of Emek Yezreel, Israel.


Department of Medicine, Padeh Medical Center, Poriya, affiliated with Azrieli Faculty of Medicine, Bar Ilan University, Safed, Israel.


Erectile dysfunction (ED) is a syndrome associated with endothelial dysfunction, which may predict cardiovascular events in men presenting with this syndrome. It has been shown to be associated with a higher rate of acute myocardial infarction and cardiovascular mortality, vascular inflammation, and impaired endothelial function. In this review we present the literature findings and describe the mechanistic pathways that are known to be involved in this syndrome and its related clinical consequences.

PMID: 31280511


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