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How Does VENDYS Work?
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![Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from [VENDYS] vascular reactivity index assessment](https://static.wixstatic.com/media/dac531_5285607cc591409a9d83746f042af7c6~mv2.png/v1/fill/w_334,h_250,fp_0.50_0.50,q_35,blur_30,enc_avif,quality_auto/dac531_5285607cc591409a9d83746f042af7c6~mv2.webp)
![Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from [VENDYS] vascular reactivity index assessment](https://static.wixstatic.com/media/dac531_5285607cc591409a9d83746f042af7c6~mv2.png/v1/fill/w_327,h_245,fp_0.50_0.50,q_95,enc_avif,quality_auto/dac531_5285607cc591409a9d83746f042af7c6~mv2.webp)
Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from [VENDYS] vascular reactivity index assessment
Ren Fail.2025 Dec;47(1):2581940. Wen-Lin Lo  , Bang-Gee Hsu , Chih-Hsien Wang , Yu-Lin Lin , Chiu-Huang Kuo ,  Yu-Hsien Lai Abstract Background: Patients with maintenance hemodialysis (MHD) present endothelial dysfunction (ED), which is characterized by impaired vasodilation and a pro-inflammatory state. Lipoprotein(a) (Lp(a)) has pro-inflammatory and pro-atherogenic properties. No study has investigated the association between serum Lp(a) and ED in patients with MHD. T


Elevated Serum Trimethylamine N-Oxide Predicts Impaired Vascular Reactivity in Patients with Hypertension
Diagnostics (Basel). 2025 Sep 20;15(18):2400. I-Min Su , Ji-Hung Wang , Chin-Hung Liu , Bang-Gee Hsu  Abstract Background/Objectives : Trimethylamine N-oxide (TMAO), a gut microbiota-derived metabolite influenced by diet, has been linked to cardiovascular disease. Endothelial dysfunction, an early sign of vascular damage, is common in hypertension. This study examined the relationship between serum TMAO levels and endothelial function, assessed by the vascular reactivity


Association of Endothelial Dysfunction With Chronic Marijuana Smoking and THC-Edible Use
JAMA Cardiol.2025 Aug 1;10(8):851-855. Leila Mohammadi, Mina Navabzadeh, Nerea Jiménez-Téllez, Daniel D Han, Emma Reagan, Jordan...


Vascular dysfunction is associated with major adverse cardiovascular events in prediabetes: A cohort study
PLoS One. 2025 Jun 5;20(6):e0324945. Dariya Kozlova , Colin Gimblet , Linder Wendt , Sadaf Akbari , Adeyinka Taiwo , Sanjana Dayal...


Guardians of the sea: molecular and biochemical adaptations in sharks and whales for atherosclerosis resistance and their potential in human cardioprotection
Raymond Rubianto Tjandrawinata , Isabela Caiado Caixeta Vencio , Axel Brahmantyo Maynardo Nugroho  Jonathan Hartanto , Nicolas Daniel...


Metabolic-dysfunction associated steatotic liver disease and atrial fibrillation: A review of pathogenesis
Inderjeet Singh Bharaj , Ajit Singh Brar , Jasraj Kahlon , Anmol Singh , Priya Hotwani , Vikash Kumar , Aalam Sohal ,  Akash Batta...


The Interplay Between Pulmonary Hypertension and Atrial Fibrillation: A Comprehensive Overview
Pulmonary hypertension (PH) and atrial fibrillation (AF) are more than just coexisting conditions—they’re interconnected through a complex web of shared molecular mechanisms and risk factors. A new comprehensive review explores how endothelial dysfunction, inflammation, oxidative stress, and other cellular processes drive this dangerous duo, contributing to poor outcomes and limited treatment options.


Impaired Neurovascular Coupling in Metabolic Syndrome: An fNIRS study
Impairments in NVC of the frontal cortex may be an early cerebrovascular mechanism underpinning cognitive decline in MetS and is discernible during higher cognitive loads. Peripheral endothelial dysfunction may be implicated in this mechanism.


Targeting Mitochondrial Dysfunction to Prevent Endothelial Dysfunction and Atherosclerosis in Diabetes: Focus on the Novel Uncoupler BAM15
Woong Bi Jang, Vinoth Kumar Rethineswaran, Sang-Mo Kwon Int J Mol Sci .2025 May 11;26(10):4603. Abstract Diabetes mellitus is a chronic...
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