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How Does VENDYS Work?
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Hyperleptinemia Is a Risk Factor for the Development of Vascular Reactivity Impairment in Patients with Hypertension
I-Min Su , Li-Liang Chuang , Ji-Hung Wang , Bang-Gee Hsu Medicina (Kaunas).2025 Nov 28;61(12):2132. Abstract Background and Objectives : Endothelial dysfunction represents an early indicator of cardiovascular disease in individuals with hypertension. Leptin, an adipokine that regulates vascular homeostasis and metabolism, has been linked to vascular impairment; however, its relationship with vascular reactivity in hypertensive patients remains unclear. Materials and Met


Serum 25-Hydroxyvitamin D Level Is Positively Associated with Vascular Reactivity Index in Patients with Type 2 Diabetes Mellitus
Bang-Gee Hsu, Yi-Cheng Wang, Du-An Wu, Ming-Chun Chen Abstract Circulating 25-hydroxyvitamin D (25(OH)D) significantly influences endothelial function. This study assessed the correlation between serum 25(OH)D and endothelial function using the vascular reactivity index (VRI) in patients with type 2 diabetes mellitus (T2DM). Fasting blood samples from 102 T2DM participants and VRI were assessed. Patients were divided into three categories based on VRI: low (VRI < 1.0), interm
![Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from [VENDYS] vascular reactivity index assessment](https://static.wixstatic.com/media/dac531_5285607cc591409a9d83746f042af7c6~mv2.png/v1/fill/w_333,h_250,fp_0.50_0.50,q_35,blur_30,enc_avif,quality_auto/dac531_5285607cc591409a9d83746f042af7c6~mv2.webp)
![Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from [VENDYS] vascular reactivity index assessment](https://static.wixstatic.com/media/dac531_5285607cc591409a9d83746f042af7c6~mv2.png/v1/fill/w_326,h_245,fp_0.50_0.50,q_95,enc_avif,quality_auto/dac531_5285607cc591409a9d83746f042af7c6~mv2.webp)
Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from [VENDYS] vascular reactivity index assessment
Ren Fail.2025 Dec;47(1):2581940. Wen-Lin Lo , Bang-Gee Hsu , Chih-Hsien Wang , Yu-Lin Lin , Chiu-Huang Kuo , Yu-Hsien Lai Abstract Background: Patients with maintenance hemodialysis (MHD) present endothelial dysfunction (ED), which is characterized by impaired vasodilation and a pro-inflammatory state. Lipoprotein(a) (Lp(a)) has pro-inflammatory and pro-atherogenic properties. No study has investigated the association between serum Lp(a) and ED in patients with MHD. T


Elevated Serum Trimethylamine N-Oxide Predicts Impaired Vascular Reactivity in Patients with Hypertension
Diagnostics (Basel). 2025 Sep 20;15(18):2400. I-Min Su , Ji-Hung Wang , Chin-Hung Liu , Bang-Gee Hsu Abstract Background/Objectives : Trimethylamine N-oxide (TMAO), a gut microbiota-derived metabolite influenced by diet, has been linked to cardiovascular disease. Endothelial dysfunction, an early sign of vascular damage, is common in hypertension. This study examined the relationship between serum TMAO levels and endothelial function, assessed by the vascular reactivity


Relationship Between Serum Myostatin and Endothelial Function in Non-Dialysis Patients with Chronic Kidney Disease
Diseases .2024 Dec 13;12(12):328. Ho-Hsiang Chang , Chih-Hsien Wang , Yu-Li Lin , Chiu-Huang Kuo , Hung-Hsiang Liou , Bang-Gee Hsu...


Increased serum galectin-3 level is associated with endothelial dysfunction and cardiovascular events in patients with hypertension
Heliyon .2024 Dec 10;11(1):e41111. Hui-Sheng Wang , Bang-Gee Hsu , Ji-Hung Wang , Chiu-Fen Yang Abstract Background: Endothelial...


Retinal and peripheral vascular function in healthy individuals with low cardiovascular risk
Abstract Objective: To assess retinal and peripheral microvascular function in individuals with low cardiovascular risk. Methods and...


The Effect of Bariatric Surgery on Microvascular Structure and Function, Peripheral Pressure Waveform and General Cardiovascular Risk: A Longitudinal Study
Abstract Purpose: This study aims to assess the effect of bariatric surgery on retinal microvascular calibre, peripheral microvascular...


Serum N-Terminal Pro-B-Type Natriuretic Peptide Level is Negatively Associated with Vascular Reactivity Index by Digital Thermal Monitoring in Patients with Hypertension
Rev Cardiovasc Med .2024 Jun 14;25(6):214 Abstract Background: B-type natriuretic peptide (BNP) coordinates endothelial homeostasis and...
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