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Hyperleptinemia Is a Risk Factor for the Development of Vascular Reactivity Impairment in Patients with Hypertension
I-Min Su , Li-Liang Chuang , Ji-Hung Wang , Bang-Gee Hsu Medicina (Kaunas).2025 Nov 28;61(12):2132. Abstract Background and Objectives : Endothelial dysfunction represents an early indicator of cardiovascular disease in individuals with hypertension. Leptin, an adipokine that regulates vascular homeostasis and metabolism, has been linked to vascular impairment; however, its relationship with vascular reactivity in hypertensive patients remains unclear. Materials and Met


Serum 25-Hydroxyvitamin D Level Is Positively Associated with Vascular Reactivity Index in Patients with Type 2 Diabetes Mellitus
Bang-Gee Hsu, Yi-Cheng Wang, Du-An Wu, Ming-Chun Chen Abstract Circulating 25-hydroxyvitamin D (25(OH)D) significantly influences endothelial function. This study assessed the correlation between serum 25(OH)D and endothelial function using the vascular reactivity index (VRI) in patients with type 2 diabetes mellitus (T2DM). Fasting blood samples from 102 T2DM participants and VRI were assessed. Patients were divided into three categories based on VRI: low (VRI < 1.0), interm
![Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from [VENDYS] vascular reactivity index assessment](https://static.wixstatic.com/media/dac531_5285607cc591409a9d83746f042af7c6~mv2.png/v1/fill/w_333,h_250,fp_0.50_0.50,q_35,blur_30,enc_avif,quality_auto/dac531_5285607cc591409a9d83746f042af7c6~mv2.webp)
![Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from [VENDYS] vascular reactivity index assessment](https://static.wixstatic.com/media/dac531_5285607cc591409a9d83746f042af7c6~mv2.png/v1/fill/w_326,h_245,fp_0.50_0.50,q_95,enc_avif,quality_auto/dac531_5285607cc591409a9d83746f042af7c6~mv2.webp)
Lipoprotein(a) levels predict endothelial dysfunction in maintenance hemodialysis patients: evidence from [VENDYS] vascular reactivity index assessment
Ren Fail.2025 Dec;47(1):2581940. Wen-Lin Lo , Bang-Gee Hsu , Chih-Hsien Wang , Yu-Lin Lin , Chiu-Huang Kuo , Yu-Hsien Lai Abstract Background: Patients with maintenance hemodialysis (MHD) present endothelial dysfunction (ED), which is characterized by impaired vasodilation and a pro-inflammatory state. Lipoprotein(a) (Lp(a)) has pro-inflammatory and pro-atherogenic properties. No study has investigated the association between serum Lp(a) and ED in patients with MHD. T


Elevated Serum Trimethylamine N-Oxide Predicts Impaired Vascular Reactivity in Patients with Hypertension
Diagnostics (Basel). 2025 Sep 20;15(18):2400. I-Min Su , Ji-Hung Wang , Chin-Hung Liu , Bang-Gee Hsu Abstract Background/Objectives : Trimethylamine N-oxide (TMAO), a gut microbiota-derived metabolite influenced by diet, has been linked to cardiovascular disease. Endothelial dysfunction, an early sign of vascular damage, is common in hypertension. This study examined the relationship between serum TMAO levels and endothelial function, assessed by the vascular reactivity


The Impact of Marijuana on the Cardiovascular System: A Review of the Most Common Cardiovascular Events Associated with Marijuana Use
Zara Latif , Nadish Garg J Clin Med .2020 Jun 19;9(6):1925. Abstract With the expanded legalization of marijuana, its medical and...


Association of Endothelial Dysfunction With Chronic Marijuana Smoking and THC-Edible Use
JAMA Cardiol.2025 Aug 1;10(8):851-855. Leila Mohammadi, Mina Navabzadeh, Nerea Jiménez-Téllez, Daniel D Han, Emma Reagan, Jordan...


Vascular dysfunction is associated with major adverse cardiovascular events in prediabetes: A cohort study
PLoS One. 2025 Jun 5;20(6):e0324945. Dariya Kozlova , Colin Gimblet , Linder Wendt , Sadaf Akbari , Adeyinka Taiwo , Sanjana Dayal...


Guardians of the sea: molecular and biochemical adaptations in sharks and whales for atherosclerosis resistance and their potential in human cardioprotection
Raymond Rubianto Tjandrawinata , Isabela Caiado Caixeta Vencio , Axel Brahmantyo Maynardo Nugroho Jonathan Hartanto , Nicolas Daniel...


Metabolic-dysfunction associated steatotic liver disease and atrial fibrillation: A review of pathogenesis
Inderjeet Singh Bharaj , Ajit Singh Brar , Jasraj Kahlon , Anmol Singh , Priya Hotwani , Vikash Kumar , Aalam Sohal , Akash Batta...
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